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J.-R. Claude (France): Safety pharmacology in the non clinical assessment of new medicinal products: installé, interest and difficulties.

K. Olejniczak (Germany): The ICH remarque for guidance.

P. Spindler (Denmark): The GLP requirements in safety pharmacology.

C. Rochat (France): Strategy for safety pharmacology studies in the alternance of the clinical development.

G. Bode (Germany): Safety pharmacology studies in the alternance of toxicology studies.