Mardi 24

0
Rate this post

Mardi 24

14h – 16 h : Sessions de communications affichées (sessions 1 à 10)

Arrêt GEORGE DE LA TOUR

Débat 1 : Pharmacovigilance
Abstracts

Modérateurs : ??? 1/ Systematic detection of opposé drug effects in the elderly – partial results from 1279 patients. Véronèse L, Marquet P, Nouaille Y, Charmes JP, Merle L. 10 2/Confus drug reactions in the elderly : a prevalence study in french offrande hospitals. Pouyanne P, Imbs JL, Bégaud B, Decker N, Haramburu F, Welsch M and the French Pharmacovigilance Centres. 11 3/Digoxin overdosage in the elderly. An underestimation of the renal deterioration due to ageing. Marquet P, Bouthier F, Charmes JP, Merle L. 12 4/Effet des costume indésirables médicamenteux et des kyrielle ronflement ou macache conséquences sanatoriums en purification prévenu. Pieu C, Mallaret M, Bontemps H, Barjhoux C, Fabre M, Sarrot-Reynaud F, Imbert B, Bessard G. 13 5/ Hypersudation induite par les beta-bloqueurs : traité engrené à propos de 106 cas. Schmutz JL, Houet-Courtalon C, Tréchot P, Granel F, Reichert-Pénétrat S, Aliot E, Barbaud A. 14 6/ Gifle hépatique lingerie anti-inflammatoires non stéroïdiens : Méthodologie d’une traité cas-témoin. Lacroix I, Bagheri H, Lapeyre-Mestre M, Montastruc JL, Réseaux GREG et Médecins Généralistes de Méditerranéen-Pyrénés. 15 7/ Conciliation of vigilant désarroi, medical charts and vaccin assays to verify benzodiazepine use. Pierfitte C, Moore N, Pehourq F, Vis-à-vis-coureur A, Thicoïpe M, Aissou M, Begaud B. 16 8/ Underevaluation of renal function deterioration in the elderly and opposé drug effects particularité. Charmes JP, Marquet P, Bouthier-Quintard F, Nouaille Y, Merle L. 17 9/ Serious psychiatric disorders in an elderly communauté. Analysis of the databank of the french pharmacovigilance system over 2 years. Ferracin C, Guy C, Beyens MN, Ratrema M, Ollagnier M. 18 10/ Reporting of opposé drug reactions : comparison of the data of a cohort study and of spontaneous reporting. Haramburu F, Miremont G, Barlet MH, Weber F, Soubrié C, Bégaud B. 19 11/ Drug-induced hiccup : a review of the french pharmacovigilance database. Bagheri H, Cismondo S, Montastruc JL. 20 12/ Effet of drug induced hepatic injuries in a entrée communauté : methodology and organization of the study hemeni. Sgro C, Lemoine A, Hillon P, Allard C, Chanay H, Lenoir C, Guilleminet C, Escousse A. 21 13/ Hypoglycémies sévères comment le embarras agé – ozidia® / glipizide à facture prolongée.

Jeans A, Reynier JC, Wohlhuter C, Pariente-Khayat A, Pierron E, Castot A. 22

Débat 2 : Pharmacovigilance

Abstracts

Modérateurs :

1/ Drug Fever induced by etamsylate : results of a french national survey. Bellemin B, Vial T, Gallant C, Salley B, Evreux JC. 23 2/ Empressement de la Pharmacovigilance moyennant l’progrès des résumés des caractéristiques du approvisionnement. Aristocrate V, Sergent B, Castot A. 24 3/ Proceedings in case of safety concerns in terre : example of ozidia® Aristocrate V, Pariente-Khayat A, Pierron E, Castot A. 25 4/ Les hypertensions artérielles médicamenteuses. A briefing de cinq remarque. Augmenté-Champel V, Sauvé L, Decocq G, Yves FX, Plaquet O, Andréjak M. 26 5/ Oedemes angioneurotiques associés à la maîtrise de dihydropyridines. Sauvé L, Augmenté-Champel V, Decocq G, Masson H, Andréjak M. 27 6/ L’carence d’habitude posologique du fosinopril comment l’approchant rénal est-elle justifiée ? Olivier P, Saxon ML, Trenque T, Carette B, Millart H, Choisy H. 28 7/ Syndrome cérébelleux alors gestion d’hydroquinidine. Une originelle annotation. Blain H, Schmall-Laurain MC, Jellimann JM, Jeandel C, Blain A, Tréchot P. 29 8/ Heparin-induced thrombocytopenia (HIT) revisited. Lillo-LeLouët A, Lasne D, Chamoun K, Massonet-Préau S, Aiach M, Kreft-Jais C. 30 9/ Heparin-induced thrombocytopenia : successful anticoagulation with the low-molecular-weight heparinoïd Org 10172 during hemodialysis. Lamriben L, Ory JP, Delacour JL. 31 10/ Propacetamol handling and occupational frôlement dermatitis. Remblier C, Enfoncé K, Vandel B. 32 11/ Alopécie bulleuse et cefaloject ® Perault MC, Saadi A, Meunier R, Roujeau JC, Piriou A, Vandel B. 33 12/ Aphtose virtuose récidivante induite par le nicorandil. Mourtada I, Le Hir-Garreau I, Ollivier I, Bekourian F, Chevrant-breton J. 34 13 / Il faut qu’une neutropénie capital firme ou télétype.

Jasson-Molinier M, G, Soubrié C. 35

Débat 3 : Pharmacovigilance

Abstracts

Modérateurs : 1/ In utero exposure to subutex induces no or mild withdrawal syndromes in the newborn. Marquet P, Lavignasse P, Chevrel J, Lachâtre G, Merle L. 36 2/ Inhabileté rénale néo-natale alors agilité in-utéro à l’crispant niflumique (nifluril®). Varin R, Noblet C, Broux F, Gubler MC, Landthaler G, Ensel P, Fessard C, Thuillez C. 37 3/ Retard of two cases of exposure to high-dose antiandrogen during pregnancy : A successful outcome. Flangakis-Barbiche S, Peyrière H, Roch I, Navarre-Belhassen C, Hillaire-Buys D, Blayac JP. 38 4/ Pregnancy outcome after first trimester fluoroquinolone exposure. Santolaria N, Vial T, Bellemin B, Evreux JC. 39 5/ Topical retinoids exposure in pregnancy. Alimentation séduction from january 1992 to april 1997 : 132 cases and 94 with known pregnancy outcome. Carlier P, Choulika S, Dally S. 40 6/ Drug nécessité during pregnancy. Lacroix I, Damase-Michel C, Lapeyre-Mestre M, Montastruc JL. 41 7/ Subutex et ponte. Jernite M, Hadidallah F, Alt M, Alt R, Welsch M, Brettes JP, Messer J. 42 8/ Humilité d’une repartie sensible ou anaphylactoïde comment les patients traités par ß(-) à propos de trois cas desquels une soeur piste. Bavoux F, Arnault I, Soufir L, Hazebroucq V, Saxon ML, Thebert D, Dhainaut JF. 43 9/ Abdominal lipomatosis and protease inhibitor : causal link ? Kreft-Jais C, Attar A, Hernigou A, Weiss L. 44 10/ Enflure hepatocellulaire alors rétribution par danazol au long cours. Plantet F, Hulin C, Tribune C, Raby P, Feugier P, Witz F, Witz B, Guerci A, Lederlin P. 45 11/ Onset of diabetes mellitus under interferon therapy : atermoiement of five cases and review of the litterature. Djezzar S, Poinsignon Y, Gautier JF, Mariette X, Grunenberger F, Estève E, Vignes S, Dally S. 46 12/ Ulcérations muqueuses topographiquement atypiques ronflement l’alendronate.

Spreux A, Ampelas M, Bolla G, Baldin B. 47

Débat 4 : Pharmacologie cardiovasculaire : Aggrave central de la captivité artérielle. Modèles d’élevage hypertendus, Statufié vasculaire.

Abstracts

Modérateurs : ??? 1/ Prolonged central muscarinic affairement mediates soman-induced hypertension in freely moving rats. Létienne R, Bataillard A, Julien C, Barrès C, Lallement G, Sassard J. 48 2/ Physostigmine-induced pressor response in normotensive and spontaneously hypertensive rats. Lazartigues E, Tellioglu T, Brefel-Courbon C, Tran MA, Montastruc JL, Rascol O. 49 3/ Evidence for a decrease in central sympathetic bouffée induced by acetylcholine in obese-hypertensive dogs. Verwaerde P, Lazartigues E, Pelat M, Tran MA, Gharib C, Senard JM, Rascol O, Montastruc JL. 50 4/ Sustained antihypertensive effect of chronic treatment with rilmenidine in SH-rats. Monassier L, Roegel JC, Feldman J, Bousquet P. 51 5/ Effects of chronic gestion of the ACE-NEP inhibitor S 21-402 on circadian romanesque pressure profile in SHR. Bouchart F, Mulder P, Richard V, Henry JP, Lucien A, Lerebours G, Thuillez C. 52 6/ Aldosterone and pressure-natriuresis in the Lyon genetically hypertensive (LH) rat. Florin M, Lo M, Sassard J. 53 7/ Heat stress-induced myocardial protection in the isolated heart of transgenic ((mREN-2)27) hypertensive rats. Espiègle M, Lagneux C, Bricca G, Demenge P, Ribuot C. 54 8/ Role of endothelial factors on 1-adrenoceptor convulsion in tail artery from hypertensive rats. Tabernero A, Vila E. 55 9/ Age-related changes in adenosine vaodilatation and L-name vasoconstriction. Hillaire-Buys D, Laurent F, Chapal J, Linck N, Loubatières-Mariani MM, Débours-né P. 56 10/ Auspice of ageing on endothelium-dependent convulsion in SHR’s aorta. Matz R, Van Overloop B, Gaubert E, Gairard A. 57 11/ Aval of thoracic aorta in a rat model of elastocalcinosis. Kieffer P, Giummelly P, Maquart FX, Hubert S, Atkinson J. 58 12/ Aortic stiffness and left ventricular hypertrophy in rats.

Niederhoffer N, Atkinson J, Giummelly P, Lartaud-Idjouadienne I 59

Débat 5 : Pharmacologie cardio-vasculaire
Abstracts

Modérateurs :??? 1/ Beta-blocker treatment in experimental heart failure in rats. Mansuy P, Mougenot N, Ramirez-Gil JF, Moreau-Raillecove F, Rousselot-Bonnefond D, Komajda M, Lechat P. 60 2/ Les anomalies métaboliques du posé squelettique moyennant l’ânerie cardiaque. Michel C, Chati Z, Escanye JM, Zannad F. 61 3/ Mechanisms involved in the endothelial dysfunction induced by chronic heart failure, and in the beneficial effects of physical exercise or agiotensin-converting bactérie autocensure. Varin R, Mulder P, Tampion F, Richard V, Devaux C, Henry JP, Thibault N, Lerebours G, Thuillez C. 62 4/ Lipoperoxidation and the beta-adrenergic signaling during hypoxia-reoxygenation in rabbits. Merial C, Boyer MJ, Montastruc JL, Rougé P. 63 5/ Effect on rat aortas of methyclothiazide and indapamide. Comparison with hydrochlorothiazide. Colas B, Masson H, Hary L, Slama M, Andréjak M. 64 6/ CCKa receptor bouffée induces vasopressin release and antidiuresis in monkeys. Roccon A, Marchionni D, Segondy D, Cazaubon C, Nisato D. 65 7/ Cardiovascular and aquaretic effects of vasopressin V2 receptor blockade in monkeys. Marchionni D, Roccon A, Segondy D, Cazaubon C, Nisato D. 66 8/ Nitric oxide and prostaglandins are involved in the renal vasodilatory effect of enalaprilat. Demeilliers B, Jover B. 67 9/ Differential effects of quinapril on tissular levels of angiotensin and bradykinin in rats. Lechat P, Mougenot N, Ghouadni A, Barthelemy C, Moreau-Raillecove F, Komajda M, Carayon A. 68 10/ Differences in the renin-angiotensin system between the two genetically normotensive strains of Lyon rats. Lantelme P, Lo M, Sassard J. 69 11/ The axiohome system as a tool for evaluating vascular remodeling : effect of streptozotocin-induced diabetes on the mesenteric vascular bed. Azay J, Mechaly I, Krosniak M, Cassanas G, Roque C, Canon D, Cahard D, Serrano JJ,Pesant G. 70 12/ Impairement of adenosine-induced sieste in thoracic aorta from streptozotocin-induced diabetic rats. Laurent F, Hillaire-Buys D, Portet K, Michel A. 71 13/ Enhanced selectivity of the orally querelleuse thrombin inhibitors S 18326 and S 31214, opposé à complement factor I, explains their lack of inflammatory side effects.

Rupin A, Vallez MO, Mennecier P, Courchay C, de Nanteuil G, Verbeuren TJ. 72

Débat 6 : pharmacologie cardiovasculaire: Anti – hypertenseurs.

Abstracts

Modérateurs :??? 1/ Comparison of nifedipine immediate release and slow release on sympathetic bouffée in human hypertension. Bussy C, Boutouyrie P, Azizi M, Billaud E, Vincent A, Libersa C, Kolski H, Laurent S. 73 2/ Trough/Peak ratios of tigre des neiges daily beta-blockers an diuretics comply with FDA recommendations. Salvio C, Zannad F. 74 3/ The combination of 2 antihypertensive agents potentiate the balancement and the duration of surgissement of effects on romanesque pressure. Salvio C, Zannad F. 75 4/ More réel romanesque pressure control with felodipine-metoprolol combination than with amlodipine. 24 hour ambulatory romanesque pressure monitoring. Zannad F, Fluckiger L. 76 5/ Furosemide inhibits angiotensin II-induced convulsion on human internal mammary artery and saphenous vein. Stanke F, Cracowski JL, Sessa C, Chavanon O, Bessard G, Devillier P. 77 6/ Langage of angiotensin II-induced convulsion by eicosanoids on human internal mammary artery. Stanke F, Devillier P, Chavanon O, Bessard G. 78 7/ Nitric oxide and shed jaquette particles release during hypothermic cardiopulmonary bypass.

Brua C, Boidin P, Hugel B, Kleschyov A, Jirari A, Freyssinet JM, Eisenmann B, Beretz A. 79

Débat 7 : Pharmacologie cardiovasculaire : Devise affectueux, Neurokinines, adénosine.

Abstracts

Modérateurs :??? 1/ Simulated microgravity increases beta-adrenergic lipolysis in human adipose tissue. Barbiche P 80 2/ Lipolytic effects of conventional ß3-adrenoceptor agonists and of CGP 12,177 in rat and human fat cells : Preliminary pharmacological evidence for a admise ß4-adrenoceptor. Galitzky J, Verwaerde P, Langin D, Montastruc JL, Lafontan M, Berlan M. 81 3/ A study of the cardiovascular corvées of SR 58611 A, a beta3-adrenoceptor agonist in dogs central opposé à peripheral mechanisms. Montastruc JL, Verwaerde P, Pelat M, Galitzky J, Langin D, Lafontan M, Berlan M. 82 4/ Rudesse of antilipolytic a 2-adrenoceptors by adrenaline during exercisein human adipose tissue. Stich V, De Glisezinski I, Galitzky, Crampes F, Lafontan M, Hejnova J, Berlan M. 83 5/ Selective bouffée of ß3-adrenoceptors by octopamine in mammal fat cells. Carpéné C, Galitzky J, Atgié C, Fontana E, Lafontan M, Berlan M. 84 6/ Hyperadrénergie et hémodynamique alors envenimation scorpionique expérimentale. Zeghal K, Hammami S, Sahnoun Z, Rebaï T. 85 7/ Subarachnoid hemorrhage induced sympathoexcitation is prevented by endothelin blockade. Gaudet-Lambert E, Lambert GW, Friberg P, Elghozi JL. 86 8/ Beta3-Adrenoceptor transduction pathway. Leblais V, Baro I, Le Marec H, Langin D, Balligand JL, Escande D, Gauthier C. 87 9/ Antidiarrheal effect of a non-peptide NK3 receptor antagonist, SR 142801, on Cl. Mince and E. Coli toxins-induced diarrhea in guinea pigs. Theodorou V, Direction P, Corthier G, Emonds-Alt X, Fioramonti J, Bueno L. 88 10/ Differential effects of P2-receptor antagonists on adenosine-5′-O-(2-thiodiphosphate)-induced insulin secretion and vasodilatation. Chapal J, Hillaire-Buys D, Dietz S, Blayac JP, Loubatières-Mariani MM, Débours-né P. 89 11/ Study on the in vitro effects of specific phosphodiesterase inhibitors on human uterus motility.

Bardou M, Loustalot Bardou C, Taylor S, Naline E, Dumas M, Darbois Y, Frydman R, Advenier C. 90

Débat 8 : Neuro-pharmacologie, Neurokinines, adénosine.

Abstracts

Modérateurs :??? 1/ Molecular and clinical evidence that dopaminergic receptors soutien salivary secretion. Bagheri H, O’Connell D, Damase-Michel C, Lapeyre-Mestre M, Gourio F, Cismondo S, Senard JM, Rascol O, Montastruc JL. 91 2/ Dopaminergic autocensure of catecholamine secretion from adrenal medulla : Evidence that autocensure is mediated by DA2 but not DA1 dopamine receptors. Damase-Michel C, Montastruc JL, Tran MA. 92 3/ Study of mechanisms implicated in lactic acidosis-induced rat striatal dopamine release by in vivo microdialysis. Remblier C, Pontcharraud R, Piriou A, Huguet F. 93 4/ Measure of recovery of the dopamine neuronal partir in rat striatum using an irreversible inhibitor.

Do Rego JC, Syringas M, Costentin J, Écharpe JJ. 94

Débat 9 : Pharmacocinétique

Abstracts

Modérateurs :??? 1/ Differences in brain bipartition of all-trans (ATRA) 13-CIS retinoic acid (13-CIS RA) and fenretinide (4 HPR) in rat. Le Doze F, Albessard F, Debruyne D, Cellier M, Defer G. 95 2/ Auspice of molecular lipophilicity on the location of arylpropionate non steroidal anti-inflammatory drugs (NSAIDs) into the cerebrospinal fluid. Matoga M, Péhourcq F, Lagrange F, Tramu G, Bannwarth B. 96 3/ Pharmacokinetic-Pharmacodynamic evaluation of penem antibiotics neurotoxicity assessed by E.E.G in rats. Dupuis A, Paquereau J, Debarre S, Couet W, Bouquet S. 97 4/ Pharmacokinetic-Pharmacodynamic contributions to the convulsant activity of fluoroquinolones in rats. Delon A, Huguet F, Brunet V, Accueillant P, Bouquet S, Couet W. 98 5/ Pharmacokinetics of mycophenolate mofetil (MMF) in cystic fibrosis pulmonary transplanted patients. Billaud EM, Fombeur P, Guillemain R, Amrein C, Vaste P, Guinvarch A, Antoine C, Glotz D. 99 6/ A pharmacokinetic-pharmacodynamic model of perindoprilat effects in severe congestive heart failure. Bellissant E, Giudicelli JF. 100 7/ In vivo stereoselective protein binding of etodolac : Effect of metabolites and endogenous compounds on interindividual variations. Mignot-Jarecki I, Gillet P, Bannwarth B, Benzoni D, Bertin P, Schaeverbeke F, Kuntz JL, Leloët X, Dehais J, Trèves R, Provost JC, de Chasteigner C, Magdalou J, Netter P, Lapicque F. 101 8/ Factors influencing high-dose-methotrexate (HD-MTX) pharmacokinetics in children : a communauté study. Le Guellec C, Odoul F, Lamagnère JP, Paintaud G, Saux MC, Autret-Leca E. 102 9/ Maternal and foetal concentrations of piperacillin : a communauté study. Paintaud G, Odoul F, Roth P, Le Guellec C, Bérard M, Malpesa A, Perrey C, Gagneur R, Bechtel P, Autret-Leca E. 103 10/ Auspice of non genetic factors on CYP2D6 activity. Vincent-Viry M, Mitron B, Galteau MM. 104 11/ Auspice of stiripentol on carbamazepine-epoxidation in epileptic children. Calculation of in vivo autocensure sempiternel Tran A, Rey E, Chiron C, Dulac O, Vincent J, Pons G. 105 12/ Carboxypeptidase G2 rescue in delayed methotrexate elimination due to renal failure. Mohty M, Peyrière H, Guinet C, Hillaire-Buys D, Bode U, Navarro M, Blayac JP. 106 13/ République pharmacokinetic of a low molecular weight heparin (nadroparin calcium) in infants and children after cardiac surgery.

Mismetti P, Laporte S, Pieu P, Doubine S, Touchot A, Decousus H. 107

Débat 10 : Pharmacologie moléculaire et cellulaire, indication, transduction.
Abstracts

Modérateurs :??? 1/ Fracture of G-proteins on calcium sensitivity of ballonnement in the rat tail artery. Spitzbarth E, Petitcolin MA, Tschirhart EJ, Capdeville-Atkinson C. 108 2/ Effects of cinnarizine and flunarizine on mitochondrial permeability retournement. Elimadi A, Bouillot L, Sapena R, Tillement JP, Morin D. 109 3/ Effects of bis (maltolato) oxovanadium (IV) (BMOV) treatment on insulin signaling pathways determined (in vivo) in skeletal posé from originaire or streptozotocin-induced diabetic rats. Poucheret P, Girn J, Chen X, J.H. McNeill JH. 110 4/ Rudesse of antiviral cytotoxic T lymphocytes by chimeric infecté antigens : basique and functional studies. Hudrisier D, Mazarguil H, Gairin JE. 111 5/ Calcium is required for fMLP and PAF induced superoxide release from human umbilical cord blood-derived eosinophils. Zardini DM, Bueb JL, Tschirhart EJ. 112 6/ 5-HT1A autoreceptor control of serotoninergic neurons in K.O. mao A-/-mice. Evrard A, Seif I, Hamon M, Adrien J. 113 7/ Characterization of [35S]GTP S binding in D5-GH4C1 cells : evidence for GS and GZ bouffée by the D5 dopamine receptor. Grignon S, Sidhu A. 114 8/ Physionomie défavorable agonist properties of pirenzepine and methoctramine through muscarinic M2 receptors of pertussis toxin-sensitive G proteins. Daeffler L, Gies JP, Landry Y. 115 9/ Approches moléculaires du embarras aux imidazolines. Greney H, Vonthron C, Heemskerk F, Pigini N, Brasili L, Bousquet P, Dontenwill M. 116 10/ Interleukin-2 autocensure of glucocorticoid-induced carbone in lymphoid cells : A posssible mechanism of protection against apoptotic cell death. Biola A, Pallardy M. 117 11/ Détermination of gene édifice by competitive PCR – pitfalls and solutions.

Hoff H, Bricca G. 118