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Abstracts Strasbourg 2004

Type présentation Jour(s) N° Session Auteurs Titre Adresses
Orale Lundi 26    1 O01 H Bagheri (1); A Dugue (1); M Lapeyre-Mestre (1); L Sailler (2); JP Thouvenot (3); R Salvayre (4); JL Montastruc (1); Detection and incidence of muscular adverse reactions: a prospective analysis from laboratorty signals 
Abstract complet
(1) Centre de Pharmacovigilance, Faculté de médecine, Toulouse; (2) Medecine Interne, CHU Purpan, Toulouse; (3) Laboratoire de Biochimie, CHU Purpan, Toulouse; (4) Laboratoire de Biochimie, CHU Rangueil, Toulouse;
Orale Lundi 26    1 O02 ML Laroche (1); S Crepin (1); O Chaput (1); L Merle (1); Adverse effects of generic drugs 
Abstract complet
(1) Centre Régional de Pharmacovigilance, Hôpital Dupuytren, Limoges;
Orale Lundi 26    1 O03 A Pathak (1); JF Tournamille (1); JM Senard (1); JL Montastruc (1); M Lapeyre (1); Diabetes increases the risk of drug-induced torsades de pointes: evidence from a french pharmacovigilance database 
Abstract complet
(1) Service de Pharmacologie Clinique, CRPV, Toulouse;
Orale Lundi 26    1 O04 M Zenut (1); S Dromnelle (1); J Lecadet (2); A Jacquet (3); R Dumas (1); J Fialip (1); C Fournier (1); D Lamaison (1); A Eschalier (1); Safety monitoring of a new meningococcal C vaccine during vaccine campain in Puy-de-Dôme county 
Abstract complet
(1) Centre Régional de Pharmacovigilance, Faculté de Médecine, Clermont Ferrand; (2) Direction du Service Médical de la région Auvergne, CNAMTS, Clermont Ferrand; (3) Unité de Pharmacovigilance, AFSSaPS, Saint-Denis;
Orale Lundi 26    1 O05 L Bensouda (1); AP Jonville-Bera (1); F Beau-Salinas (1); M Mayer (2); S Llabres (2); E Autret-Leca (1); Results of a French Pharmacovigilance survey on the etonogestrel contraceptive implant 
Abstract complet
(1) Service de Pharmacologie Clinique et Pharmacovigilance, CHU, Tours; (2) Unité de Pharmacovigilance, Laboratoire Organon, Puteaux;
Orale Lundi 26    1 O06 H Peyrière (1); M Villiet (1); V Alibert (1); M Creus (1); JP Blayac (1); D Hillaire-Buys (1); Hypoglycemia related to tramadol therapy. Analysis of cases reported in the French Pharmacovigilance database 
Abstract complet
(1) Service de Pharmacologie Médicale et Toxicologie, Hôpital Lapeyronie, Montpellier;
Orale Lundi 26    1 O07 G Girard (1); C Guy (1); MN Beyens (1); M Ratrema (1); G Mounier (1); H Decousus (2); M Ollagnier (1); Interaction between Oral Anticoagulants (OAC) and Coxibs About 17 cases notified to the French Pharmacovigilance Centers 
Abstract complet
(1) Centre de Pharmacovigilance, Hôpital Bellevue – CHU St-Etienne, Sant-Etienne; (2) Service de Médecine Interne et Thérapeutique, Hôpital Bellevue – CHU St-Etienne, Sant-Etienne;
Orale Lundi 26    2 O08 Y Bernard (1); JL Bueb (1); DR Wagner (2); EJ Tschirhart (1); Impact of oxidative stress on MMP-2 and MMP-9 activation in human coronary artery smooth muscle cells 
Abstract complet
(1) Laboratoire de Biologie et Physiologie Intégrée, Faculté des Sciences, Université du Luxembourg, Luxembourg, Luxembourg; (2) Service de Cardiologie, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg;
Orale Lundi 26    2 O09 A D’Anglemont de tassigny (1); B Ghaleh (1); R Souktani (1); P Henry (2); A Berdeaux (1); Hypoosmotic stress inhibits doxorubicin-induced apoptosis via a protein kinase A dependent mechanism in adult rabbit cardiac myocytes 
Abstract complet
(1) INSERM E 00.01, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre; (2) INSERM U 572, Hôpital Lariboisière, Paris;
Orale Lundi 26    2 O10 M Sarr (1); M Chataigneau (1); S Martins (1); C Schott (1); J El Bedoui (1); B Muller (2); VB Schini-Kerth (1); Formation of releasable NO stores by S-nitrosoglutathione in arteries exhibiting an endothelial dysfunction induced by chronic infusion of Angiotensin II 
Abstract complet
(1) UMR CNRS 7034, Faculté de Pharmacie, Illkirch; (2) EMI INSERM 0356, Faculté de Pharmacie, Bordeaux;
Orale Lundi 26    3 O11 JS Hulot (1); JM Treluyer (2); C Chiron (3); S Tonnelier (2); P Lechat (1); G Pons (2); Triangular test (TT), a sequential approach for comparative trials in children 
Abstract complet
(1) Pharmacologie, Hôpital Pitié-Salpêtrière, Paris; (2) Pharmacologie, Hôpital Cochin – Saint Vincent de Paul, Paris; (3) Neuropediatrie, Hôpital Cochin – Saint Vincent de Paul, Paris;
Orale Lundi 26    3 O12 I Berlin (1); J Medioni (2); A Mallet (2); Increased risk of relapse rate after stopping nicotine replacement therapies. A mathematical modeling approach 
Abstract complet
(1) Sce de Pharmacologie, GHU Pitié-Salpêtrière, Paris; (2) Sce de Biostatistique, Faculté de Médecine Pitié-Salpêtrière, Paris;
Orale Lundi 26    3 O13 N Picard (1); Y Le Meur (2); JC Szelag (2); P Marquet (1); Glucuronidation of mycophenolic acid (MPA): identification of the UDP-glucuronosyltransferase (UGT) isoforms producing MPA-phenyl-glucuronide and MPA-acyl-glucuronide 
Abstract complet
(1) Service de Pharmacologie et Toxicologie, CHU de Limoges, Limoges; (2) Service de Néphrologie-Hémodialyse, CHU de Limoges, Limoges;
Orale Lundi 26    3 O14 M Billing-Grima (1); C Coquard (1); J Steger (1); M Barthelmebs (1); JL Imbs (2); Dual renin-angiotensin system blockade effects on plasma and renal angiotensin II levels 
Abstract complet
(1) Institut de Pharmacologie, Faculté de Médecine, Strasbourg; (2) Service d’Hypertension, Maladies Vasculaires et Pharmacologie Clinique, Hôpitaux Universitaires, Strasbourg;
Orale Lundi 26    3 O15 F Saint-Marcoux (1); C Knoop (2); J Debord (1); P Thiry (3); A Rousseau (1); M Estenne (2); P Marquet (1); Pharmacokinetic study of tacrolimus in cystic fibrosis and non-cystic fibrosis lung transplants and design of Bayesian estimators using limited sampling strategies 
Abstract complet
(1) Department of Pharmacology-Toxicology, University Hospital, Limoges; (2) Department Chest Medicine, Erasme University Hospital, Bruxelles, Belgique; (3) Department of Clinical Chemistry, Erasme University Hospital, Bruxelles, Belgique;
Orale Lundi 26    3 O16 M Benouchan (1); F Do Nascimento (1); GY Perret (2); BM Colombo (1); Gene delivery of Escherichia coli nitroreductase into endothelial cells prolongs the survival of tumor-bearing mice treated with the prodrug CB1954 
Abstract complet
(1) UPRES 2360, Université Paris-XIII, Faculté de Médecine, Bobigny; (2) ERIT-M 0204, Laboratoire de Pharmacologie, Université Paris-XIII, Faculté de Médecine, Bobigny;
Orale Lundi 26    5 O17 S Nénan (1); JM Planquois (1); S Hitier (1); P Berna (1); E Boichot (2); V Lagente (2); CP Bertrand (1); Effects of dexamethasone, rolipram and marimastat on inflammatory response induced by local instillation of MMP-12 in mouse lungs 
Abstract complet
(1) Pfizer Global R&D, Fresnes Laboratories, Fresnes; (2) Faculté de Pharmacie, Université de Rennes 1, Rennes;
Orale Lundi 26    5 O18 V Freund (1); C Bertrand (2); C Zuany (2); N Frossard (1); NGF induces proliferation of the human airway smooth muscle cells through activation of the TrkA receptor 
Abstract complet
(1) EA 3771, Inflammation et Environnement dans l’asthme, Faculté de Pharmacie, Illkirch; (2) Pfizer Global Research and Development, Fresnes;
Orale Lundi 26    6 O19 N Niederhoffer (1); L Hein (2); K Starke (3); Modulation of the baroreceptor reflex by _lpha2A-adrenoceptors_____ 
Abstract complet
(1) INSERM U392, Faculté de Pharmacie, Illkirch; (2) Institut de Pharmacologie et de Toxicologie, Université de Würzburg, Würzburg, Allemagne; (3) Institut de Pharmacologie et de Toxicologie, Université de Freiburg, Freiburg, Allemagne;
Orale Lundi 26    6 O20 C Moro (1); J Polak (1); B Richterova (1); C Sengenès (1); T Pelikanova (1); J Galitzky (1); V Stich (1); M Lafontan (1); M Berlan (2); Differential regulation of ANP- and adrenergic receptor-dependent lipolytic pathways in human adipose tissue 
Abstract complet
(1) Laboratoire Franco-Tchèque de Recherche Clinique sur l’Obésité, Inserm U586, Toulouse; (2) Laboratoire de Pharmacologie Médicale et Clinique, Faculté de médecine, Toulouse;
Orale Mardi 27    7 O21 N Voirin (1); B Fantino (2); N Dickson (1); F Fantino (2); L Laforest (1); E Van Ganse (1); Preventive behaviour of general practitioners towards iatrogenesis of elderly patients 
Abstract complet
(1) Pharmacoepidemiology EA 3091, CHU-Lyon, Pierre-Bénite; (2) AGORAS-ADIM, Lyon;
Orale Mardi 27    7 O22 P Lochet (1); H Peyrière (2); V Le Moing (1); JP Blayac (2); S Hansel (3); J Reynes (1); Assessment of renal toxicity of tenofovir in a cohort of 107 treated-patients 
Abstract complet
(1) Service des Maladies Infectieuses et tropicales, Hôpital Gui de Chauliac, Montpellier; (2) Service de Pharmacologie Médicale et Toxicologie, Hôpital Lapeyronie, Montpellier; (3) Pharmacie, Hôpital Lapeyronie, Montpellier;
Orale Mardi 27    7 O23 G Durrieu (1); J Torello (2); P Olivier (1); JL Montastruc (1); JR Castillo (2); Coxibs and arterial hypertension: an analysis of the Spanish and French Pharmacovigilance databases 
Abstract complet
(1) Service de Pharmacologie Clinique, CRPV/Faculté de Médecine, Toulouse; (2) Centro Andaluz de Farmacovigilancia, HU Virgen del Rocio, Sevilla, Spain;
Orale Mardi 27    7 O24 T Vial (1); P Harry (2); P Eftekhari (3); H Jantzem (4); AP Jonville-Bera (5); B Mosquet (6); C Payen (1); J Descotes (1); Severe toxicity due to a drug containing diethylene glycol ethyl-ether as an excipient: report of 6 cases 
Abstract complet
(1) Centre Antipoison – Centre de Pharmacovigilance, Hospices Civils de Lyon, Lyon; (2) Centre Antipoison, CHRU, Angers; (3) Centre de Pharmacovigilance, Hôpital Fernand Widal, Paris; (4) Centre de Pharmacovigilance, Hôpital de la Cavale Blanche, Brest; (5) Centre de Pharmacovigilance, CHRU, Tours; (6) Centre de Pharmacovigilance, CHRU, Caen;
Orale Mardi 27    8 O25 FP Monnet (1); L Combettes (2); MP Morin-Surun (3); Sigma agonists affect the synaptic plasticity via an intracellular mobilization of calcium and pkc 
Abstract complet
(1) EPS Charcot, Plaisir; (2) INSERM U405, Orsay; (3) INSERM U488, Lekremlin-Bicêtre;
Orale Mardi 27    8 O26 C Brefel-Courbon (1); P Payoux (2); C Thalamas (3); M Galitzky (3); JL Montastruc (1); O Rascol (1); Levodopa raises pain threshold in Parkinson’s disease : a Clinical and Positron Emission Tomography study 
Abstract complet
(1) Service de Pharmacologie, Faculté de médecine, Toulouse; (2) INSERM U455, CHU de Toulouse, Toulouse; (3) Centre d’Investigation Clinique, CHU de Toulouse, Toulouse;
Orale Mardi 27    8 O27 P Gelé (1); S Gautier (1); A Tailleux (2); P Duriez (2); R Bordet (1); Fenofibrate treatment reduces inflammatory and oxidative states in the brain of Apolipoprotein E Knock Out mice 
Abstract complet
(1) Laboratoire de Pharmacologie, Faculté de Médecine de Lille 2, Lille; (2) INSERM U 545, Institut Pasteur et Faculté de Pharmacie de Lille2, Lille;
Orale Mardi 27    8 O28 JP Guilloux (1); B Guiard (1); F Artigas (2); M Toth (3); AM Gardier (1); Does (±)-pindolol act on 5-HT1A autoreceptors located in the Dorsal Raphé Nucleus of C57BL/6J Mice when combined with an antidepressant drug : a study in Wild-Type and 5-HT1A receptor null mutant mice 
Abstract complet
(1) Laboratoire de Neuropharmacologie EA3544, Faculté de Pharmacie, Châtenay-Malabry; (2) Department of Neurochemistry, Institut d’Investigacions Biomediques de Barcelona, Barcelona, Espagne; (3) Department of Pharmacology, Weill Medical College of Cornell University, New-York, USA;
Orale Mardi 27    8 O29 M Bourin (1); F Clenet (1); M Hascoët (1); G Fillion (1); H Gallons (2); Anxiolytic profile of 5-HT moduline antagonist in mice 
Abstract complet
(1) EA 3256, Faculté de Médecine, Nantes; (2) Faculté des Sciences Pharmaceutiques et Biologique, Paris;
Orale Mardi 27    8 O30 M Hascoët (1); F Massé (1); M Bourin (1); Antidepressive like effect of lamotrigine using the forced swimming test in mice 
Abstract complet
(1) EA 3256, Faculté de Médecine, Nantes;
Orale Mardi 27    10 O31 PH Villard (1); F Fallone (1); E Sérée (1); O Rimet (1); V Bourgarel-Rey (1); F Fouchier (1); Y Barra (1); A Durand (2); B Lacarelle (1); Repressive effect of retinoic acid toward the Ah receptor CYP1A1 induction pathway 
Abstract complet
(1) UMR CNRS 6032, Faculté de Pharmacie, Marseille; (2) Laboratoire de Toxicologie et Pharmacie Clinique, Faculté de Pharmacie, Marseille;
Orale Mardi 27    10 O32 C Delayre-Orthez (1); J Becker (1); J Auwerx (2); N Frossard (1); F Pons (1); PPARalpha decreases airway inflammation associated with asthma in the mouse 
Abstract complet
(1) EA 3771, Faculté de Pharmacie, Illkirch; (2) ICS, IGBMC, Illkirch;
Orale Mardi 27    10 O33 T Ouk (1); O Pétrault (1); P Gelé (1); M Laprais (1); S Gautier (1); P Duriez (2); M Bastide (1); R Bordet (1); Acute treatment by a PPAR-alpha agonist decreases cerebral infarct volume and prevents partly post-ischemic Kir 2.1 impairment 
Abstract complet
(1) EA 1046, Service de Pharmacologie, Faculté de Médecine, Lille; (2) INSERM U545, Institut Pasteur de Lille et Université de Lille 2, Lille;
Orale Mardi 27    13 O34 B Charbit (1); C Funck-Brentano (2); E Samain (1); P Albaladejo (1); J Marty (1); QT interval prolongation after oxytocin bolus during surgical abortion 
Abstract complet
(1) Departement d’Anesthésie Réanimation, Hôpital Beaujon, Clichy; (2) Service de Pharmacologie, Hôpital Saint-Antoine, Paris;
Orale Mardi 27    13 O35 B Baldin (1); A Dozol (1); A Spreux (1); RM Chichmanian (1); National follow-up of the cases of tuberculosis associated with infliximab 
Abstract complet
(1) Centre Régional de Pharmacovigilance, Hôpital Pasteur, 30 avenue de la voie romaine, Nice;
Orale Mardi 27    13 O36 C Bousquet (1); C Henegar (2); A Lillo-Le louët (1); MC Jaulent (2); A knowledge based approach for the description of adverse drug reactions using the MedDRA terminology 
Abstract complet
(1) Centre Régional de Pharmacovigilance, Hôpital Pompidou, Paris; (2) INSERM ERM202, Faculté de Médecine Broussais – Hôtel Dieu, Paris;
Orale Mardi 27    13 O37 Y Arimone (1); B Bégaud (1); A Fourrier-Réglat (1); G Miremont-Salamé (1); H Théophile (2); F Haramburu (1); N Moore (1); Agreement of expert judgement in adverse drug reactions causality assessment 
Abstract complet
(1) Département de Pharmacologie EA 3676, Université Bordeaux 2, Bordeaux; (2) ARME Pharmacovigilance, Université Bordeaux 2, Bordeaux;
Orale Mercredi 28    16 O38 C Kunzelmann (1); JM Freyssinet (1); MC Martinez (1); Rho A participates in the regulation of phosphatidylserine transmembrane redistribution in megakaryocytic cells 
Abstract complet
(1) INSERM 143, Faculté de Médecine, Strasbourg;
Orale Mercredi 28    16 O39 L Dupuy (1); H Greney (1); P Bousquet (1); Benazoline enhances apoptotic pc12 cells death induced by serum deprivation: an i1 imidazoline receptor dependent mechanism 
Abstract complet
(1) INSERM E-333, Faculté de Médecine, Strasbourg;
Orale Mercredi 28    19 O40 F Dupuis (1); J Atkinson (1); JM Chillon (1); Effect of telmisartan on cerebral arteriolar structure and cerebral autoregulation in spontaneously hypertensive rats 
Abstract complet
(1) Laboratoire de Pharmacologie, Faculté de Pharmacie-UHP-Nancy 1, Nancy;
Orale Mercredi 28    19 O41 L Lucats (1); V Chalvignac (1); A Bizé (1); B Ghaleh (1); A Berdeaux (1); Rapid ventricular pacing induces late preconditioning against myocardial stunning: role of radical oxygen species 
Abstract complet
(1) INSERM E 00.01, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre;
Orale Mercredi 28    19 O42 H Millart (1); A Robinet (1); G Hoizey (2); F Moreau (1); J Pisani (1); Further insight into the mechanisms of pharmacological preconditioning (PC) induced by transient beta1-adrenoceptor (beta1-AR) stimulation in the isolated perfused rat heart 
Abstract complet
(1) Laboratoire de Pharmacologie, Faculté de Médecine, Reims; (2) Laboratoire de Pharmacologie et de Toxicologie, CHU, 45 rue Cognacq-Jay, Reims;
Orale Mercredi 28    20 O43 N Lechevallier-Michel (1); A Fourrier (1); C Fabrigoule (2); JF Dartigues (2); Use of drugs with central anticholinergic effects and cognitive performance in the elderly : Results from the PAQUID Study 
Abstract complet
(1) Département de Pharmacologie EA 3676, Université Bordeaux 2, Bordeaux; (2) Unité INSERM 593, Université Bordeaux 2, Bordeaux;
Orale Mercredi 28    20 O44 E Rahme (1); K Dasgupta (1); Y Toubouti (1); AN Barkun (2); M Bardou (3); Gastrointestinal Effects of Rofecoxib and Celecoxib versus NSAIDs among Patients on Low Dose Aspirin 
Abstract complet
(1) Département d’Epidémiologie Clinique, Hôpital Général, Université McGill, Montréal, Canada; (2) Département de Gastroentérologie, Hôpital Général, Université McGill, Montréal, Canada; (3) Unité de Pharmacologie Clinique, CHU du Bocage, Dijon;
Orale Mercredi 28    20 O45 M Lapeyre-Mestre (1); I Lacroix (1); F Haramburu (2); V Auclair (2); M Mallaret (2); N Bernard (2); J Arditti (2); V Pinzani (2); C Armand-Malaplate (2); C Vigneau (2); M M Assouly (2); C Messina-Gourlot (3); Implementation of a national system for drugs of abuse monitoring : Results of the OSIAP survey “Ordonnances Suspectes Indicateur d’Abus et de Pharmacodependance” 
Abstract complet
(1) CEIP de Toulouse, EA3696, Unité de Pharmacoépidémiologie, Faculté de médecine, Toulouse; (2) Association Française des CEIP et Centres Correspondants, Faculté de Médecine, Bordeaux; (3) Unité des Stupéfiants et Psychotropes, AFSSaPS, Saint-Denis;
Orale Mercredi 28    20 O46 K Lacut (1); E Oger (1); F Couturaud (1); G Le Gal (1); D Mottier (1); Aspirin may lower the risk of venous thromboembolism: a hospital-based case-control study 
Abstract complet
(1) Département de Médecine Interne et Pneumologie, CHU, Brest;
Orale Mercredi 28    20 O47 L Laforest (1); E Van Ganse (1); G Pietri (1); Y Pacheco (2); P Ernst (3); Asthma management in family general practice in France 
Abstract complet
(1) Pharmacoepidemiology, EA 3091, CHU-Lyon, Pierre-Bénite; (2) Respiratory Medicine Department, CHU-Lyon, Pierre-Bénite; (3) Pharmacoepidemiology Unit, McGill University, Canada, Montreal, Canada;
Orale Mercredi 28    20 O48 A Laribiere (1); H Reyre (1); A Abouelfath (1); G Miremont-Salamé (1); F Haramburu (1); Vaccination campaign against C meningitis in Aquitaine (Landes and Pyrénées atlantiques): safety monitoring 
Abstract complet
(1) Hôpital Pellegrin, Centre de Pharmacovigilance, Bordeaux;
Orale Mercredi 28    20 O49 F Depont (1); A Fourrier-Réglat (1); M Amouretti (2); Y Merlière (3); M Pigeon (3); P Fender (3); P Blin (1); B Bégaud (1); N Moore (1); Methodological and logistical aspects of the CADEUS (Cox-2 and NSAIDs: Description of Users) study 
Abstract complet
(1) Departement de Pharmacologie, Université Victor Segalen Bordeaux 2, Bordeaux; (2) Service d’Hépato-Gastroentérologie, Hôpital du Haut l’Evêque, Pessac; (3) Caisse Nationale d’Assurance Maladie des Travailleurs Salariés, Service Médical, Paris;

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